Glucose- and Non-Glucose-Induced Mitochondrial Dysfunction in Diabetic Kidney Disease

Mitochondrial dysfunction plays an important role in the pathogenesis and progression of diabetic kidney disease (DKD). In this review, we will discuss mitochondrial dysfunction observed in preclinical models of DKD as well as in clinical DKD with a focus on oxidative phosphorylation (OXPHOS), mitoc...

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Bibliographic Details
Main Authors: Marie Ito, Margaret Zvido Gurumani, Sandra Merscher, Alessia Fornoni
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/3/351