An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice

Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.

Bibliographic Details
Main Authors: Sverre Grødem, Ingeborg Nymoen, Guro Helén Vatne, Frederik Sebastian Rogge, Valgerður Björnsdóttir, Kristian Kinden Lensjø, Marianne Fyhn
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36324-3