An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice
Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36324-3 |
| _version_ | 1828041608933670912 |
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| author | Sverre Grødem Ingeborg Nymoen Guro Helén Vatne Frederik Sebastian Rogge Valgerður Björnsdóttir Kristian Kinden Lensjø Marianne Fyhn |
| author_facet | Sverre Grødem Ingeborg Nymoen Guro Helén Vatne Frederik Sebastian Rogge Valgerður Björnsdóttir Kristian Kinden Lensjø Marianne Fyhn |
| author_sort | Sverre Grødem |
| collection | DOAJ |
| description | Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate. |
| first_indexed | 2024-04-10T17:18:51Z |
| format | Article |
| id | doaj.art-e8b3f8f9448d45829181003c21fbf846 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T17:18:51Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e8b3f8f9448d45829181003c21fbf8462023-02-05T12:17:07ZengNature PortfolioNature Communications2041-17232023-02-0114111310.1038/s41467-023-36324-3An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male miceSverre Grødem0Ingeborg Nymoen1Guro Helén Vatne2Frederik Sebastian Rogge3Valgerður Björnsdóttir4Kristian Kinden Lensjø5Marianne Fyhn6Center for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloCenter for Integrative Neuroplasticity, Department of Bioscience, University of OsloGenetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.https://doi.org/10.1038/s41467-023-36324-3 |
| spellingShingle | Sverre Grødem Ingeborg Nymoen Guro Helén Vatne Frederik Sebastian Rogge Valgerður Björnsdóttir Kristian Kinden Lensjø Marianne Fyhn An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice Nature Communications |
| title | An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice |
| title_full | An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice |
| title_fullStr | An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice |
| title_full_unstemmed | An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice |
| title_short | An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice |
| title_sort | updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro orbital injections in male mice |
| url | https://doi.org/10.1038/s41467-023-36324-3 |
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