BPTF promotes the progression of distinct subtypes of breast cancer and is a therapeutic target

BPTF promotes the progression of distinct subtypes of breast cancer and is a therapeutic target

PurposeTo assess the biomarker and functional role of the chromatin remodeling factor, bromodomain PHD finger transcription factor (BPTF), in breast cancer progression.MethodsBPTF copy number was assessed using fluorescence in situ hybridization. BPTF expression was regulated in breast cancer cells...

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Bibliographic Details
Main Authors: Vladimir Bezrookove, Imran A. Khan, Mehdi Nosrati, James R. Miller, Sean McAllister, Altaf A. Dar, Mohammed Kashani-Sabet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
BPTF
triple-negative
ER-positive
breast cancer
oncogene
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1011173/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1011173/full

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