Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system

Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system

TTN mutations are the common genetic cause for various types of cardiomyopathies (e.g., dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy) and skeletal myopathies. Here, we generated three TTN knock-out human induced...

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Bibliographic Details
Main Authors: Ji-Young Kang, Dasom Mun, Yumin Chun, Da-Seul Park, Hyoeun Kim, Nuri Yun, Seung-Hyun Lee, Boyoung Joung
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122002501

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http://www.sciencedirect.com/science/article/pii/S1873506122002501

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