Antiproliferative Activities and SwissADME Predictions of Physicochemical Properties of Carbonyl Group‐Modified Rotenone Analogues

Antiproliferative Activities and SwissADME Predictions of Physicochemical Properties of Carbonyl Group‐Modified Rotenone Analogues

Abstract Rotenone is a naturally occurring compound shown to exhibit antiproliferative activity against various cancer cell lines, indicating its potential as a lead anticancer agent. However, its toxicity against normal cells has prompted further investigation and chemical modifications. In this st...

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Bibliographic Details
Main Authors: Rajelle D. Hernandez, Frances Abygail F. Genio, Jannelle R. Casanova, Dr. Marlon T. Conato, Dr. Monissa C. Paderes
Format: Article
Language:English
Published: Wiley-VCH 2024-01-01
Series:ChemistryOpen
Subjects:
rotenone derivatives
anticancer
structure modification
natural products
antiproliferative
Online Access:https://doi.org/10.1002/open.202300087

Internet

https://doi.org/10.1002/open.202300087

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