Detection of circulating B cells producing anti-GPIb autoantibodies in patients with immune thrombocytopenia.

BACKGROUND: We previously reported that an enzyme-linked immunospot (ELISPOT) assay for detecting anti-GPIIb/IIIa antibody-secreting B cells is a sensitive method for identifying patients with immune thrombocytopenia (ITP). Here we assessed the clinical significance of measuring circulating B cells...

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Bibliographic Details
Main Authors: Masataka Kuwana, Yuka Okazaki, Yasuo Ikeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899372?pdf=render