Protocol to establish a stable MLL-AF9_AML mouse model
Summary: Acute myeloid leukemia (AML) is one of the most common and fatal forms of hematopoietic malignancies. Here, we describe a mouse MLL-AF9_AML model to investigate AML. We have optimized the protocols for retrovirus infection, bone marrow transplantation (BMT), and leukemia monitoring to creat...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166722004397 |