In-silico drug trials for precision medicine in atrial fibrillation: From ionic mechanisms to electrocardiogram-based predictions in structurally-healthy human atria

In-silico drug trials for precision medicine in atrial fibrillation: From ionic mechanisms to electrocardiogram-based predictions in structurally-healthy human atria

Atrial fibrillation (AF) inducibility, sustainability and response to pharmacological treatment of individual patients are expected to be determined by their ionic current properties, especially in structurally-healthy atria. Mechanisms underlying AF and optimal cardioversion are however still uncle...

Full description

Bibliographic Details
Main Authors: Albert Dasí, Aditi Roy, Rafael Sachetto, Julia Camps, Alfonso Bueno-Orovio, Blanca Rodriguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation
in-silico
drug trials
cardioversion
electrocardiogram
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.966046/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.966046/full

Similar Items