Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots in the endothelium are defined and how they are recognized by the leukocyte. Using lat...

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Bibliographic Details
Main Authors: Janine JG Arts, Eike K Mahlandt, Max LB Grönloh, Lilian Schimmel, Ivar Noordstra, Emma Gordon, Abraham CI van Steen, Simon Tol, Barbara Walzog, Jos van Rijssel, Martijn A Nolte, Marten Postma, Satya Khuon, John M Heddleston, Eric Wait, Teng Leong Chew, Mark Winter, Eloi Montanez, Joachim Goedhart, Jaap D van Buul
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
endothelium
Transmigration
protrusions
GTPase
actin
inflammation
Online Access:https://elifesciences.org/articles/66074

Internet

https://elifesciences.org/articles/66074

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