Phytosphingosine ceramide mainly localizes in the central layer of the unique lamellar phase of skin lipid model systems

Understanding the lipid arrangement within the skin’s outermost layer, the stratum corneum (SC), is important for advancing knowledge on the skin barrier function. The SC lipid matrix consists of ceramides (CERs), cholesterol, and free fatty acids, which form unique crystalline lamellar phases, refe...

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Bibliographic Details
Main Authors: Andreea Nădăban, Gerrit S. Gooris, Charlotte M. Beddoes, Robert M. Dalgliesh, Joke A. Bouwstra
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522000918