Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia caused by accumulation of multiple genetic alterations in T-cell progenitors. However, for many genes it remains unknown how their mutations contribute to disease development. Therefore, we performed two single-cell CRISP...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2024-05-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/11621 |