Downregulation of miR-146a promotes tumorigenesis of cervical cancer stem cells via VEGF/CDC42/PAK1 signaling pathway

Downregulation of miR-146a promotes tumorigenesis of cervical cancer stem cells via VEGF/CDC42/PAK1 signaling pathway

Cervical cancer (CC) is a primary gynecological malignancy worldwide. Cancer stem cells (CSCs) possess enhanced tumor-initiating and self-renewing abilities. MicroRNAs (miRNAs) play essential roles in CSCs’ tumorigenesis. This study investigated the effects of miR-146a on CSCs’ tumorigenesis and inv...

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Bibliographic Details
Main Authors: Zhihong Dong, Chunxia Yu, Kuerban Rezhiya, Aier Gulijiahan, Xinling Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Cervical cancer
cancer stem cells
MiR-146a
VEGF
tumorigenesis
invasion
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1664560

Internet

https://www.tandfonline.com/doi/10.1080/21691401.2019.1664560

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