Electrospray-Based Microencapsulation of Epigallocatechin 3-Gallate for Local Delivery into the Intervertebral Disc

Electrospray-Based Microencapsulation of Epigallocatechin 3-Gallate for Local Delivery into the Intervertebral Disc

Locally delivered anti-inflammatory compounds can restore the homeostasis of the degenerated intervertebral disc (IVD). With beneficial effects on IVD cells, epigallocatechin 3-gallate (EGCG) is a promising therapeutic candidate. However, EGCG is prone to rapid degradation and/or depletion. Therefor...

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Bibliographic Details
Main Authors: Moira Loepfe, Anja Duss, Katerina-Alexandra Zafeiropoulou, Oddny Björgvinsdóttir, Matteo D’Este, David Eglin, Giuseppino Fortunato, Juergen Klasen, Stephen J. Ferguson, Karin Wuertz-Kozak, Olga Krupkova
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
degenerative disc disease
inflammation
drug delivery
EGCG
microparticles
injectable biomaterial
electrospraying
Online Access:https://www.mdpi.com/1999-4923/11/9/435

Internet

https://www.mdpi.com/1999-4923/11/9/435

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