Cryopreservation of cerebrospinal fluid cells preserves the transcriptional landscape for single-cell analysis

Cryopreservation of cerebrospinal fluid cells preserves the transcriptional landscape for single-cell analysis

Abstract Cerebrospinal fluid (CSF) matrix biomarkers have become increasingly valuable surrogate markers of neuropsychiatric diseases in research and clinical practice. In contrast, CSF cells have been rarely investigated due to their relative scarcity and fragility, and lack of common collection an...

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Bibliographic Details
Main Authors: Mahesh Chandra Kodali, Jerry Antone, Eric Alsop, Rojashree Jayakumar, Khushi Parikh, Aude Chiot, Paula Sanchez-Molina, Bahareh Ajami, Steven E. Arnold, Kendall Jensen, Sudeshna Das, Marc S. Weinberg
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Neuroinflammation
Subjects:
Cerebrospinal fluid
Transcriptomics
10x
Single-cell
Methods
Neuroimmunology
Online Access:https://doi.org/10.1186/s12974-024-03047-1

Internet

https://doi.org/10.1186/s12974-024-03047-1

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