Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices

Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices

Ascorbic acid (AA; a.k.a. vitamin C) is well known for its cellular protection in environments of high oxidative stress. Even though physiological concentrations of AA in the brain are significant (0.2–10 mM), surprisingly little is known concerning the role of AA in synaptic neurotransmission under...

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Bibliographic Details
Main Authors: Segewkal H. Heruye, Ted J. Warren, Joseph A. Kostansek IV, Samantha B. Draves, Stephanie A. Matthews, Peter J. West, Kristina A. Simeone, Timothy A. Simeone
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Nutrients
Subjects:
high frequency oscillation
fEPSP
fiber volley
sharp wave
population spike
E-S coupling
Online Access:https://www.mdpi.com/2072-6643/14/3/613

Internet

https://www.mdpi.com/2072-6643/14/3/613

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