Dnmt3b ablation affects fracture repair process by regulating apoptosis

Abstract Purpose Previous studies have shown that DNA methyltransferase 3b (Dnmt3b) is the only Dnmt responsive to fracture repair and Dnmt3b ablation in Prx1-positive stem cells and chondrocyte cells both delayed fracture repair. Our study aims to explore the influence of Dnmt3b ablation in Gli1-po...

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Bibliographic Details
Main Authors: Xu Wang, Qinwen Ge, Qinghe Zeng, Kaiao Zou, Zhengsheng Bao, Jun Ying, Zhen Wu, Hongting Jin, Jiali Chen, Taotao Xu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-024-07283-7