A PRELIMINARY STUDY OF STEREOSELECTIVITY OF MEFLOQUINE ENANTIOMERS IN RAT
Stereoselectivity of mefloquine enantiomers were studied in rats after oral administration of a single 50mg/Kg dose of the racemate. Pharmacokinetic parameters of (+)-(RS)-MFQ in blood and plasma showed no significant difference. The concentration, AUC , CLIF and VdlF of (+)-(RS)-enantiomerin blood...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
1998-12-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/1758 |