Multiplex Label-Free Kinetic Characterization of Antibodies for Rapid Sensitive Cardiac Troponin I Detection Based on Functionalized Magnetic Nanotags

Multiplex Label-Free Kinetic Characterization of Antibodies for Rapid Sensitive Cardiac Troponin I Detection Based on Functionalized Magnetic Nanotags

Express and highly sensitive immunoassays for the quantitative registration of cardiac troponin I (cTnI) are in high demand for early point-of-care differential diagnosis of acute myocardial infarction. The selection of antibodies that feature rapid and tight binding with antigens is crucial for imm...

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Bibliographic Details
Main Authors: Alexey V. Orlov, Juri A. Malkerov, Denis O. Novichikhin, Sergey L. Znoyko, Petr I. Nikitin
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
molecular biomarkers
detection of biomolecules
superparamagnetic iron oxide nanoparticles
high-throughput sensing
cardiac markers
real-time optical biosensors
Online Access:https://www.mdpi.com/1422-0067/23/9/4474

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https://www.mdpi.com/1422-0067/23/9/4474

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