Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia

Abstract. T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy often associated with poor outcomes. To identify high-risk factors and potential actionable targets for T-ALL, we perform integrated genomic and transcriptomic analyses on samples from 165 Chinese pediatric...

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Bibliographic Details
Main Authors: Haichuan Zhu, Bingjie Dong, Yingchi Zhang, Mei Wang, Jianan Rao, Bowen Cui, Yu Liu, Qian Jiang, Weitao Wang, Lu Yang, Anqi Yu, Zongru Li, Chao Liu, Leping Zhang, Xiaojun Huang, Xiaofan Zhu, Hong Wu
Format: Article
Language:English
Published: Wolters Kluwer Health 2022-01-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000102