Autophagy-dependent ferroptosis as a potential treatment for glioblastoma

Glioblastoma (GBM) is the most common malignant primary brain tumor with a poor 5-year survival rate. Autophagy is a conserved intracellular degradation system that plays a dual role in GBM pathogenesis and therapy. On one hand, stress can lead to unlimited autophagy to promote GBM cell death. On th...

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Bibliographic Details
Main Authors: Yangchun Xie, Tao Hou, Jinyou Liu, Haixia Zhang, Xianling Liu, Rui Kang, Daolin Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1091118/full