In vitro anticancer activities, multi-spectroscopic and in silico DNA binding studies of propranolol drug and its new Zn(II) complex

In vitro anticancer activities, multi-spectroscopic and in silico DNA binding studies of propranolol drug and its new Zn(II) complex

A new Zn(II) complex of propranolol (PPN), [Zn2(PPN)2(μ-Cl)2] (ZnPPN), was synthesized and characterized using 1H NMR and FT-IR spectroscopies, CHN elemental analysis, cyclic voltammetry (CV) and conductance measurements. Then the interaction of both the drug and its Zn(II) complex with calf thymus...

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Bibliographic Details
Main Authors: Farshid Hajibabaei, Samira Sharifinia, Neda Hosseinpour Moghadam, Sadegh Salehzadeh, Katayoun Derakhshandeh, Sadegh Khazalpour
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Zn(II) complex
Propranolol
DNA interaction
Anticancer
Intercalation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622002946

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http://www.sciencedirect.com/science/article/pii/S2211715622002946

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