CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer

Tumor-associated macrophages (TAMs) are among the main contributors to immune suppression in the tumor microenvironment, however, TAM depletion strategies have yielded little clinical benefit. Here, we discuss the concept that TAMs are also key regulators of anti-PD(L)-1-mediated CD8 T cell-dependen...

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Bibliographic Details
Main Authors: Shahram Salek-Ardakani, Paola Marie Marcovecchio, Graham Thomas
Format: Article
Language:English
Published: BMJ Publishing Group 2021-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/2/e002045.full