CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer
Tumor-associated macrophages (TAMs) are among the main contributors to immune suppression in the tumor microenvironment, however, TAM depletion strategies have yielded little clinical benefit. Here, we discuss the concept that TAMs are also key regulators of anti-PD(L)-1-mediated CD8 T cell-dependen...
Main Authors: | Shahram Salek-Ardakani, Paola Marie Marcovecchio, Graham Thomas |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-02-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/9/2/e002045.full |
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