The Lipid Virulence Factors of <i>Mycobacterium tuberculosis </i>Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

The Lipid Virulence Factors of <i>Mycobacterium tuberculosis </i>Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Autophagy is an important innate immune defense mechanism that controls <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) growth inside macrophages. Autophagy machinery targets <i>Mtb</i>-containing phagosomes via xenophagy after damage to the phagosomal membrane due...

Full description

Bibliographic Details
Main Authors: Aïcha Bah, Merlin Sanicas, Jérôme Nigou, Christophe Guilhot, Catherine Astarie-Dequeker, Isabelle Vergne
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
autophagy
mycobacterium
tuberculosis
lipids
macrophage
phagosome
lysosomes
innate immunity
Online Access:https://www.mdpi.com/2073-4409/9/3/666

Internet

https://www.mdpi.com/2073-4409/9/3/666

Similar Items