Heterogenous profiles between primary lung cancers and paired brain metastases reveal tumor evolution

Heterogenous profiles between primary lung cancers and paired brain metastases reveal tumor evolution

BackgroundBrain metastases (BMs) are the most common central nervous system (CNS) malignant tumors, with rapid disease progression and extremely poor prognosis. The heterogeneity between primary lung cancers and BMs leads to the divergent efficacy of the adjuvant therapy response to primary tumors a...

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Bibliographic Details
Main Authors: Yanming Chen, Xiaoxiao Dai, Ji Wang, Chuming Tao, Ye Wang, Qing Zhu, Zhongyong Wang, Tan Zhang, Qing Lan, Jizong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
heterogeneity
brain metastasis
lung cancer
gene mutation
evolution
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1026099/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1026099/full

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