Molecular genetic analysis of Type II diabetes associated m.3243A>G mitochondrial DNA mutation in a Pakistani family

Molecular genetic analysis of Type II diabetes associated m.3243A>G mitochondrial DNA mutation in a Pakistani family

Background: Type II diabetes is the most often considered as maternally inherited disease and A>G transition at position 3243 of mitochondrial DNA (m.3243A>G) in the encoding tRNALeu (UUR) gene is thought to be strongly responsible for the pathogenesis of the disease in number of cases. Aim: C...

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Bibliographic Details
Main Authors: Saidul Abrar, Khushi Muhammad, Hasnain Zaman, Suleman Khan, Faisal Nouroz, Nousheen Bibi
Format: Article
Language:English
Published: SpringerOpen 2017-07-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Type II diabetes
Mitochondrial DNA
PCR
DNA sequencing
m.3243A>G
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863016300805

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http://www.sciencedirect.com/science/article/pii/S1110863016300805

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