Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation
Abstract The impact of Tim-3 (T cell immunoglobulin and mucin domain-containing protein 3) on cisplatin-induced acute kidney injury was investigated in this study. Cisplatin-induced Tim-3 expression in mice kidney tissues and proximal tubule-derived BUMPT cells in a time-dependent manner. Compared w...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-07-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01519-6 |