Effect of NLRP3 inflammasome genes polymorphism on disease susceptibility and response to TNF-α inhibitors in Iraqi patients with rheumatoid arthritis

Effect of NLRP3 inflammasome genes polymorphism on disease susceptibility and response to TNF-α inhibitors in Iraqi patients with rheumatoid arthritis

Background: Rheumatoid arthritis (RA) is a genetically predisposed, systemic, chronic, inflammatory disease. Immune system dysregulation and inherited susceptibility polymorphisms suggest that this type of variation is functional and may help predict disease susceptibility and develop new therapeuti...

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Bibliographic Details
Main Authors: Abdullah Abbas Awni, Zainab Oday Hamed, Ahmed Abdul-Hassan Abbas, Ahmed Sahib Abdulamir
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Rheumatoid arthritis
Etanercept
Infliximab
IL-1β
TNF-α
NLRP3
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023040215

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http://www.sciencedirect.com/science/article/pii/S2405844023040215

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