Evaluation of the Effect of an Intraperitoneal Cytostatic-Loaded Supramolecular Hydrogel on Intestinal Anastomotic Healing in an Animal Model

Evaluation of the Effect of an Intraperitoneal Cytostatic-Loaded Supramolecular Hydrogel on Intestinal Anastomotic Healing in an Animal Model

The prognosis of colorectal cancer patients with peritoneal metastases is very poor. Intraperitoneal drug delivery systems, like supramolecular hydrogels, are being developed to improve local delivery and intraperitoneal residence time of a cytostatic such as mitomycin C (MMC). In this study, we eva...

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Bibliographic Details
Main Authors: Danique J. I. Heuvelings, Anne G. W. E. Wintjens, Audrey C. H. M. Jongen, Maurits J. C. A. M. Gielen, Kaatje Lenaerts, Peter-Paul K. H. Fransen, Marion J. Gijbels, Geert C. van Almen, Patricia Y. W. Dankers, Ignace H. J. T. de Hingh, Nicole D. Bouvy
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Life
Subjects:
peritoneal metastases
colorectal cancer
intraperitoneal delivery
injectable supramolecular hydrogel
mitomycin C
Online Access:https://www.mdpi.com/2075-1729/13/10/2076

Internet

https://www.mdpi.com/2075-1729/13/10/2076

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