MOV10L1 Binds RNA G-Quadruplex in a Structure-Specific Manner and Resolves It More Efficiently Than MOV10

Summary: MOV10L1 and its paralog MOV10 are evolutionally conserved RNA helicases involved in distinct RNA regulatory pathways. The testis-specific MOV10L1 is essential for spermatogenesis and PIWI-interacting RNAs biogenesis, whereas MOV10 is ubiquitous and multifunctional. Although both proteins ha...

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Bibliographic Details
Main Authors: Xia Zhang, Lina Yu, Shasha Ye, Jie Xie, Xingxu Huang, Ke Zheng, Bo Sun
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301981