Impact of Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibody C1q-Binding Ability on Kidney Allograft Outcome

Impact of Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibody C1q-Binding Ability on Kidney Allograft Outcome

The consolidation of single antigen beads (SAB-panIgG) assay in the detection of preformed anti-human leukocyte antigen (HLA) antibodies has improved transplantation success. However, its high sensitivity has limited the allograft allocation for sensitized patients, increasing their waiting time. A...

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Bibliographic Details
Main Authors: Juan Molina, Ana Navas, María-Luisa Agüera, Cristian Rodelo-Haad, Corona Alonso, Alberto Rodríguez-Benot, Pedro Aljama, Rafael Solana
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
allograft-loss risk
C1q-binding antibodies
kidney allograft survival
kidney transplantation
preformed anti-HLA antibodies
single antigen beads assay
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01310/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01310/full

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