Preclinical and clinical studies of a tumor targeting IL-12 immunocytokine

The clinical success of immune checkpoint inhibitors (ICIs) has demonstrated the promise and challenges of cancer immunotherapy. There is an unmet need to develop novel cancer therapies that can provide clinical benefit for most patients with solid malignancies, which harbor innate or acquired resis...

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Bibliographic Details
Main Authors: Christine M. Minnar, Grace Lui, James L. Gulley, Jeffrey Schlom, Sofia R. Gameiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1321318/full