The CB1 cannabinoid receptor antagonist rimonabant chronically prevents the nicotine-induced relapse to alcohol

The CB1 cannabinoid receptor antagonist rimonabant chronically prevents the nicotine-induced relapse to alcohol

Preclinical and clinical research shows that the cannabinoid brain receptor type 1 (CB1) modulates alcohol- and nicotine-related behaviors. Throughout the nicotine-induced relapse to alcohol, the rats were pre-treated for 10 days with the CB1 cannabinoid receptor antagonist rimonabant (0, 0.03, 0.3...

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Bibliographic Details
Main Authors: José Antonio López-Moreno, Gustavo González-Cuevas, Miguel Navarro
Format: Article
Language:English
Published: Elsevier 2007-02-01
Series:Neurobiology of Disease
Subjects:
Nicotine
Relapse to alcohol
Rimonabant
Operant self-administration
Cannabinoid system
Sucrose
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002385

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http://www.sciencedirect.com/science/article/pii/S0969996106002385

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