Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways

Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways

Considerable emphasis is being placed on combinatorial chemotherapeutic/natural treatments for breast cancer. This study reveals the synergistic anti-tumor activity of morin and Doxorubicin (Dox) co-treatment on MDA-MB-231 triple-negative breast cancer (TNBC) cell proliferation. Morin/Dox treatment...

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Bibliographic Details
Main Authors: Sushma Maharjan, Min-Gu Lee, So-Young Kim, Kyu-Shik Lee, Kyung-Soo Nam
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceuticals
Subjects:
morin
MDA-MB-231 triple-negative breast cancer (TNBC)
doxorubicin
synergistic effect
FOXM1
EGFR/STAT3
Online Access:https://www.mdpi.com/1424-8247/16/5/672

Internet

https://www.mdpi.com/1424-8247/16/5/672

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