Genetic Background of Polycythemia Vera

Genetic Background of Polycythemia Vera

Polycythemia vera belongs to myeloproliferative neoplasms, essentially by affecting the erythroblastic lineage. JAK2 alterations have emerged as major driver mutations triggering PV-phenotype with the <i>V617F</i> mutation detected in nearly 98% of cases. That’s why JAK2 targeting therap...

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Bibliographic Details
Main Authors: Mathilde Regimbeau, Romain Mary, François Hermetet, François Girodon
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
polycythemia vera
<i>JAK2</i> mutation
erythrocytosis
myeloproliferative neoplasm
mutational landscape
Online Access:https://www.mdpi.com/2073-4425/13/4/637

Internet

https://www.mdpi.com/2073-4425/13/4/637

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