Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer

Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer

Abstract Background Immune checkpoint inhibitors (ICIs) have altered the clinical management of non-small cell lung cancer (NSCLC). However, the low response rate, severe immune-related adverse events (irAEs), and hyperprogressive disease following ICIs monotherapy require attention. Combination the...

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Bibliographic Details
Main Authors: Dingyi Yu, Penghui Yang, Xiaoyan Lu, Shaoze Huang, Li Liu, Xiaohui Fan
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cell Communication and Signaling
Subjects:
Non-small cell lung cancer
Single-cell RNA sequencing
Programmed death-1 inhibitor
Shenmai injection
Natural killer cells
Online Access:https://doi.org/10.1186/s12964-023-01184-3

Internet

https://doi.org/10.1186/s12964-023-01184-3

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