Development of fast dispersing tablets of nebivolol: experimental and computational approaches to study formulation characteristics

Development of fast dispersing tablets of nebivolol: experimental and computational approaches to study formulation characteristics

Formulation of FDT (fast dispersing tablets) of nebivolol was optimized and evaluated using simplex lattice design (SLD). The influence of type and concentration of three disintegrants viz.,Ac-Di-Sol, Primojel and Polyplasdone XL on hardness, friability and disintegration time of tablet was studied....

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Bibliographic Details
Main Authors: Rajamma Abburu Jayaramu, Sateesha Shivally Boregowda, Addanki Rahul Deva Varma, Chandan Kalegowda
Format: Article
Language:English
Published: Universidade de São Paulo 2014-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Nebivolol/comprimidos de dispersão rápida
Planejamento de grade simplex
Comprimidos de dispersão rápida/capacidade de intumescimento
Comprimidos de dispersão rápida/capacidade de hidratação
Comprimidos de dispersão rápida/tempo de decomposição
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400956&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400956&lng=en&tlng=en

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