Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model

Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model

COVID-19 cases caused by new variants of highly mutable SARS-CoV-2 continue to be identified worldwide. Effective control of the spread of new variants can be achieved through targeting of conserved viral epitopes. In this regard, the SARS-CoV-2 nucleocapsid (N) protein, which is much more conserved...

Full description

Bibliographic Details
Main Authors: Alexandra Rak, Nikolay Gorbunov, Valeria Kostevich, Alexey Sokolov, Polina Prokopenko, Larisa Rudenko, Irina Isakova-Sivak
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
SARS-CoV-2
nucleocapsid phosphoprotein
monoclonal antibody
immunogenicity
recombinant protein
cross-reactivity
Online Access:https://www.mdpi.com/1999-4915/15/1/230

Internet

https://www.mdpi.com/1999-4915/15/1/230

Similar Items