Cardiac physiologic regulation of sub-type specific adrenergic receptors in transgenic mice overexpressing β1- and β2-adrenergic receptors

Cardiac physiologic regulation of sub-type specific adrenergic receptors in transgenic mice overexpressing β1- and β2-adrenergic receptors

Objective Combination of β1-adrenergic receptor (AR) blockade and β2-AR activation might be a potential novel therapy for treating heart failure. However, use of β-AR agonists and/or antagonists in the clinical setting is controversial because of the lack of information on cardiac inotropic or chron...

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Bibliographic Details
Main Authors: Ka Eul Kim, Hyun-Jin Tae, Petrashevskaya Natalia, Jae-Chul Lee, Ji Hyeon Ahn, Joon Ha Park, In Hye Kim, Taek Geun Ohk, Chan Woo Park, Jun Hwi Cho, Moo-Ho Won
Format: Article
Language:English
Published: The Korean Society of Emergency Medicine 2016-09-01
Series:Clinical and Experimental Emergency Medicine
Subjects:
adrenergic receptors
transgenic mice
isoproterenol
inotropic
chronotropic
Online Access:http://www.ceemjournal.org/upload/pdf/ceem-16-141.pdf

Internet

http://www.ceemjournal.org/upload/pdf/ceem-16-141.pdf

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