Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling.
Altered vitamin D signaling is associated with cardiac dysfunction, but the pathogenic mechanism is not clearly understood. We examine the mechanism and the role of vitamin D signaling in the development of cardiac dysfunction.We analyzed 1α-hydroxylase (1α-OHase) knockout (1α-OHase-/-) mice, which...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4182450?pdf=render |