Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21<sup>high</sup> Cells In Vivo
P21 and p16 have been identified as inducers of senescence. Many transgenic mouse models have been developed to target cells expressing high levels of <i>p16<sup>Ink4a</sup></i> (p16<sup>high</sup>) and investigate their potential contribution to tissue dysfunctio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-03-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/6/5565 |