Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications

Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process, is predominantly associated with low back pain and permanent disability. Pyroptosis is a type of lytic programmed cell death triggered by the activation of inflammasomes and caspases. Unlike apoptosis, pyr...

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Bibliographic Details
Main Authors: Jieya Luo, Yuxuan Yang, Xuan Wang, Xingyu Chang, Songbo Fu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/12/1804