The Oncogene IARS2 Promotes Non-small Cell Lung Cancer Tumorigenesis by Activating the AKT/MTOR Pathway

The Oncogene IARS2 Promotes Non-small Cell Lung Cancer Tumorigenesis by Activating the AKT/MTOR Pathway

A limited number of studies have indicated an association between isoleucyl-tRNA synthetase 2 (IARS2) and tumorigenesis. We evaluated IARS2 protein expression in lung tumor tissues and paired non-tumor tissues. We found higher IARS2 expression in the tumor tissues, which was associated with the late...

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Bibliographic Details
Main Authors: Xin Di, Xin Jin, He Ma, Ruimin Wang, Shan Cong, Chang Tian, Jiaying Liu, Min Zhao, Ranwei Li, Ke Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
isoleucyl-tRNA synthetase 2
lung cancer
tumorigenesis
cDNA microarray
ingenuity pathway analysis
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00393/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00393/full

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