Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

Abstract Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships between DNAm age and A-ECG heart age and to understand...

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Bibliographic Details
Main Authors: Constantin-Cristian Topriceanu, Eesha Dev, Mahmood Ahmad, Rebecca Hughes, Hunain Shiwani, Matthew Webber, Kenan Direk, Andrew Wong, Martin Ugander, James C. Moon, Alun D. Hughes, Jane Maddock, Todd T. Schlegel, Gabriella Captur
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Clinical Epigenetics
Subjects:
Advanced electrocardiography
Aging
DNA methylation age
Online Access:https://doi.org/10.1186/s13148-023-01576-9

Internet

https://doi.org/10.1186/s13148-023-01576-9

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