Discovery of Novel 1,2,3-triazole Derivatives as IDO1 Inhibitors

Indoleamine 2,3-dioxygenase 1 (IDO1) has received much attention as an immunomodulatory enzyme in the field of cancer immunotherapy. While several IDO1 inhibitors have entered clinical trials, there are currently no IDO1 inhibitor drugs on the market. To explore potential IDO1 inhibitors, we designe...

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Bibliographic Details
Main Authors: Xixi Hou, Xiaoqing Gong, Longfei Mao, Jie Zhao, Jianxue Yang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/11/1316