Autism-associated protein POGZ controls ESCs and ESC neural induction by association with esBAF

Abstract Background The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs), particularly autism spectrum disorder (ASD) and intellectual disability (ID). However, little is known about its roles in embryonic stem cells (ESCs), neural development and diseases. Methods...

Full description

Bibliographic Details
Main Authors: Xiaoyun Sun, Linxi Cheng, Yuhua Sun
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Autism
Online Access:https://doi.org/10.1186/s13229-022-00502-9