Autism-associated protein POGZ controls ESCs and ESC neural induction by association with esBAF
Abstract Background The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs), particularly autism spectrum disorder (ASD) and intellectual disability (ID). However, little is known about its roles in embryonic stem cells (ESCs), neural development and diseases. Methods...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | Molecular Autism |
Online Access: | https://doi.org/10.1186/s13229-022-00502-9 |