Non-linear Dose Response of Lymphocyte Cell Lines to Microtubule Inhibitors

Non-linear Dose Response of Lymphocyte Cell Lines to Microtubule Inhibitors

Microtubule (MT) inhibitors show anti-cancer activity in a wide range of tumors in vitro and demonstrate high clinical efficacy. To date they are routinely included into many chemotherapeutic regimens. While the mechanisms of MT inhibitors’ interactions with tubulin have been well-established, the r...

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Bibliographic Details
Main Authors: Daria M. Potashnikova, Aleena A. Saidova, Anna V. Tvorogova, Eugene V. Sheval, Ivan A. Vorobjev
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
cell cycle
cell death
microtubule inhibitors
paclitaxel
nocodazole
vinorelbine
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00436/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00436/full

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