Rapid and effective preparation of clonal bone marrow-derived mesenchymal stem/stromal cell sheets to reduce renal fibrosis

Abstract Allogeneic “off-the-shelf” mesenchymal stem/stromal cell (MSC) therapy requires scalable, quality-controlled cell manufacturing and distribution systems to provide clinical-grade products using cryogenic cell banking. However, previous studies report impaired cell function associated with a...

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Bibliographic Details
Main Authors: Sumako Kameishi, Celia M. Dunn, Masatoshi Oka, Kyungsook Kim, Yun-Kyoung Cho, Sun U. Song, David W. Grainger, Teruo Okano
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31437-7