Extrachromosomal circular DNA: a new potential role in cancer progression

Abstract Extrachromosomal circular DNA (eccDNA) is considered a circular DNA molecule that exists widely in nature and is independent of conventional chromosomes. eccDNA can be divided into small polydispersed circular DNA (spcDNA), telomeric circles (t-circles), microDNA, and extrachromosomal DNA (...

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Bibliographic Details
Main Authors: Tianyi Wang, Haijian Zhang, Youlang Zhou, Jiahai Shi
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-02927-x